Formin nucleates the growth of parallel actin bundles in the cell. Additionally, myosin motor activity is positively regulated by phosphorylation. The monomeric G protein RhoA is important in cytokinesis, because it directly or indirectly …
A) activates formins and inactivates myosin light-chain phosphatase.
B) inactivates formins and activates myosin light-chain kinases.
C) activates formins as well as myosin light-chain phosphatases.
D) inactivates formins as well as myosin light-chain kinases.
E) None of the above.

Question

Quizplus · Accepted Answer

This G protein activates formin as well as multiple protein kinases, including the Rho-activated kinase Rock. Rock phosphorylates regulatory myosin light chains and also inhibits myosin light-chain phosphatase by phosphorylation.

Formin Nucleates the Growth of Parallel Actin Bundles in the Cell