The role of Chordin and Noggin in patterning in developing vertebrates is equivalent to that of …(1) in Drosophila. They are secreted from the …(2) pole and antagonize the activity of bone morphogenetic factors that are secreted throughout the embryo.
A) 1: Decapentaplegic; 2: dorsal
B) 1: Decapentaplegic; 2: ventral
C) 1: Short gastrulation; 2: dorsal
D) 1: Short gastrulation; 2: ventral

Question

Quizplus · Accepted Answer

Like their Drosophila counterpart Sog, Noggin and Chordin antagonize the proteins of the bone morphogenetic protein (BMP) family (Decapentaplegic is a family member in the fruit fly). However, unlike Sog, Noggin and Chordin limit BMP activity to the ventral (rather than the dorsal) side of the embryo. This results in the inversion of the D-V axis in vertebrates compared to that of insects.

The Role of Chordin and Noggin in Patterning in Developing