Which group of factors is thought to impede iPS cell generation from a differentiated cell, inasmuch as the reprogramming efficiency is increased when the activity of the factors is decreased?
A) Histone acetyl transferases
B) Histone deacetylases
C) Chromatin remodelers
D) DNA demethylases
E) All of the above

Question

Quizplus · Accepted Answer

Generally, activation of chromatin remodelers, histone acetyl transferases, and DNA demethylases leads to less repressive chromatin states that are more permissive for reprogramming. As expected from their activities, histone acetyl transferases and deacetylases have opposite effects on reprogramming efficiency.

Which Group of Factors Is Thought to Impede IPS Cell