To screen a colony of bacteria for a particular gene you would

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Using a probe is the most specific and efficient method for screening a colony of bacteria for a particular gene. Probes are short strands of DNA or RNA that are complementary to a specific gene or sequence. They can be labeled with a signal, such as a fluorescent tag, and used to detect the presence of the target gene in a sample. This method does not require any manipulation or modification of the target DNA, making it less invasive than methods such as gel electrophoresis or restriction enzyme analysis.

To Screen a Colony of Bacteria for a Particular Gene