A state of hypercoagulability can be caused by all of the following except:

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Depleted vitamin K actually leads to a state of hypocoagulability, or decreased ability to clot. The other choices, obesity, smoking, and SLE, can all contribute to a state of hypercoagulability. Depleted vitamin K would actually cause hypocoagulability, as vitamin K is necessary for the production of clotting factors. Obesity, smoking, and autoimmune diseases such as SLE can all lead to a state of hypercoagulability.

A State of Hypercoagulability Can Be Caused by All of the Following