The most common sign of folate deficiency is:

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The most common sign of folate deficiency is megaloblastic anemia, which is characterized by abnormally large red blood cells. This is due to impaired DNA synthesis in cells. While microcytic anemia and hemolytic anemia may also result from nutrient deficiencies, they are not the most common signs of folate deficiency. Pernicious anemia is caused by a deficiency in vitamin B12, not folate. Megaloblastic anemia is a condition characterized by enlarged, immature red blood cells due to impaired DNA synthesis. Folate is essential for DNA synthesis and a deficiency can result in megaloblastic anemia. Microcytic anemia is caused by iron deficiency, pernicious anemia is caused by a deficiency in vitamin B12, and hemolytic anemia is caused by the destruction of red blood cells.

The Most Common Sign of Folate Deficiency Is