In vegans, the deficiency of vitamin B₁₂ may be masked by the high intake of folate.

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Vegans who consume high levels of folate may appear to have adequate levels of vitamin B12 due to the similarities in the symptoms of deficiency, but this does not mean that their B12 status is actually sufficient. It is important for vegans to supplement with B12 to prevent a deficiency. This is true. Folate can mask a B₁₂ deficiency because both vitamins are involved in the production of red blood cells. High folate intake can improve the symptoms of anemia caused by B₁₂ deficiency but does not cure the underlying problem. Vegans who do not consume fortified foods or supplements may still develop neurological complications of B₁₂ deficiency despite having normal folate levels. Therefore, it is recommended that vegans supplement with B₁₂ to avoid deficiency.

In Vegans, the Deficiency of Vitamin B₁₂ May Be Masked