Botulism Is a Type of Paralysis (Inability to Move Muscles)

Botulism is a type of paralysis (inability to move muscles) caused by a specific type of bacteria. The bacteria release a toxin that prevents the release of acetylcholine (a neurotransmitter) from the neurons that form synapses with muscle cells. Why might botulism toxin cause paralysis?

A) Without acetylcholine, action potentials never get to muscles cells because they cannot move from one node of Ranvier to the next.
B) Since acetylcholine is responsible for establishing the concentration gradient of sodium ions, action potentials cannot form in the neurons of individuals with botulism.
C) If acetylcholine is not released, action potentials that stimulate muscle contraction cannot be transmitted across the synaptic cleft to muscle cells.
D) In the absence of acetylcholine, sensory neurons are unable to communicate with motor neurons so motor neurons never receive the signal to cause muscle contraction.