How Can the Significance of Human Involvement Be Assessed in This

How can the significance of human involvement be assessed in this current mass extinction event?

A) by using scientific methods to examine extinction patterns in locations where human activities or their impacts vary.
B) Since it is impossible to determine what caused any past extinction there is no basis to judge the significance of human activities at this present time
C) No method can reliably work because simply measuring human involvement is sufficiently disruptive to cause the observed extinctions.
D) by prohibiting all recreational hunting, fishing, hiking, and other intrusions into natural areas and observing the response.