When cells are stimulated to divide,

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During cell division, tumor suppressors are inactivated, allowing the cell to divide. Normal function of tumor suppressors is to inhibit cell division and promote DNA repair. When these genes are inactivated, cell division can occur unchecked, potentially leading to cancer. Proto-oncogenes, on the other hand, are activated during cell division and become oncogenes if they acquire mutations that cause them to be overactive, promoting uncontrolled cell division.

When Cells Are Stimulated to Divide