Evidence obtained from family, twin, and genetic studies of mood disorders tells us that

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Family, twin, and genetic studies have consistently shown that genes play a role in the development of mood disorders, including major depression. While there is no single "depression gene," certain genetic variations have been associated with an increased risk for the disorder. Additionally, family studies have shown that individuals with a first-degree relative who has major depression are at an increased risk for developing the disorder themselves. However, the risk is not near perfect prediction for suicide among family members - while genetics can play a role in suicidal behavior, it is a complex phenomenon influenced by many factors.

Evidence Obtained from Family, Twin, and Genetic Studies of Mood