Muscular dystrophy is a group of inherited disorders that lead to increasing muscle cell loss and thus muscle weakness over time. There are many different types of muscular dystrophy. Symptoms can vary, although all involve muscle weakness. Duchenne muscular dystrophy (DMD) is a recessive X-linked form that leads to muscle degeneration and death usually by age 25. Symptoms begin before age 5 and include low endurance and difficulties standing. As the condition progresses, muscle tissue is replaced with adipose and other types of connective tissue. Abnormal bone development and some neurobehavioral and learning disabilities may also occur. DMD occurs as a result of a mutation in a single gene on the X chromosome. This gene codes for a particular protein, dystrophin, which plays a major role in the structure of muscle cells. The protein formed by the mutated gene is nonfunctional, and the absence of a functional protein eventually leads to cell death. In producing the protein dystrophin, DNA is __________ to RNA and then __________ to a protein in the cytoplasm of the cell.

Question

Quizplus · Accepted Answer

The process of producing proteins from DNA involves transcription, where DNA is transcribed to RNA, followed by translation, where RNA is translated to a protein.

Muscular Dystrophy Is a Group of Inherited Disorders That Lead