At what stage of chronic kidney disease will levels of creatinine and blood urea nitrogen (BUN)first begin to increase?

Name: At what stage of chronic kidney disease will levels of creatinine and blood urea nitrogen (BUN)first begin to increase?
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Stage III is characterized by increased albumin levels in the urine and decreased in the blood, resulting in noticeable edema. During this stage, levels of creatinine and BUN increase, resulting in accumulation of waste products in the blood called azotemia.

At What Stage of Chronic Kidney Disease Will Levels of Creatinine