The principal reaction that prepares fatty acids for use as energy is

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Beta-oxidation is the process of breaking down fatty acids into acetyl CoA molecules that can be used in the citric acid cycle to produce ATP. This process occurs in the mitochondria of cells and is the primary reaction that prepares fatty acids for use as energy. Deamination is the removal of an amino group from an amino acid, hydrolysis is the breakdown of a molecule using water, and dehydration synthesis is the process of joining two molecules together by removing a water molecule. While these reactions can occur during the metabolism of fatty acids, they are not the primary reactions that prepare fatty acids for use as energy.

The Principal Reaction That Prepares Fatty Acids for Use as Energy