Testosterone secretion is regulated by
A) concentration of FSH in the blood
B) a positive feedback mechanism involving the hypothalamus
C) rate of spermatogenesis in the seminiferous tubules
D) temperature of the interstitial cells
E) a negative feedback mechanism involving the hypothalamus

Question

Quizplus · Accepted Answer

Testosterone secretion is regulated by a negative feedback mechanism involving the hypothalamus. When testosterone levels in the blood rise, it signals the hypothalamus to decrease the secretion of gonadotropin-releasing hormone (GnRH), which in turn decreases the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by the pituitary gland. This leads to a decrease in testosterone secretion by the testes. Conversely, when testosterone levels in the blood fall, it signals the hypothalamus to increase the secretion of GnRH, which stimulates the pituitary gland to increase secretion of LH and FSH, leading to an increase in testosterone secretion by the testes.

Testosterone Secretion Is Regulated by