A patient presents with loss of reflexes,foot drop and ataxia.The drugs most likely to cause these problems are the _______________.

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Vinca alkaloids, such as vincristine and vinblastine, are known to cause neurotoxicity, which can manifest as loss of reflexes, foot drop, and ataxia. Antimetabolites (such as methotrexate), alkylating agents (such as cyclophosphamide), and topoisomerase inhibitors (such as etoposide) are not typically associated with these neurological symptoms.

A Patient Presents with Loss of Reflexes,foot Drop and Ataxia