A Friend of Yours Has Just Turned 40 and He

A friend of yours has just turned 40 and he is asking you whether or not he should have a PSA test done as part of his annual physical exam. What would you tell him?

A) Definitely yes, because along with a rectal exam, PSA is likely to prevent prostate cancer.
B) Yes, because along with treatment, his chances of surviving prostate cancer will be greatly increased.
C) No, because current research shows that a positive PSA test does not correlate at all with prostate cancer.
D) You should tell him to look at the research literature and have a discussion with his physician about the relative risks versus potential benefits of PSA screening.