Methotrexate is an alkylating agent that works by binding to the DNA of rapidly growing cells and preventing the replication of DNA.

Name: Methotrexate is an alkylating agent that works by binding to the DNA of rapidly growing cells and preventing the replication of DNA.
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Methotrexate is a folate antagonist that works by inhibiting the enzyme dihydrofolate reductase, which is necessary for the synthesis of DNA precursors. It does not directly bind to DNA.

Methotrexate Is an Alkylating Agent That Works by Binding to the DNA