Androgen insensitivity syndrome is typically diagnosed when:

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Androgen insensitivity syndrome (AIS) is a condition where a person who is genetically male (with XY chromosomes) is resistant to male hormones (called androgens). As a result, the person has some or all of the physical traits of a woman, but the genetic makeup of a man. Diagnosis often occurs when menstruation does not occur in a teenager who has the external appearance of a female, because individuals with complete AIS have testes that produce normal amounts of male hormones, but their bodies are unable to respond to these hormones. This leads to the development of female external genitalia and the absence of menstruation due to the lack of a uterus.

Androgen Insensitivity Syndrome Is Typically Diagnosed When