Exhibit 6A This is a reaction going on in your muscle cells right this very minute: The enzyme triose phosphate isomerase catalyzes this reaction in the forward direction as part of the glycolytic pathway. It follows simple Michaelis-Menten kinetics:
Typical cellular concentrations: triose phosphate isomerase = 0.1 nM
Dihydroxyacetone phosphate = 5 µM glyceraldehyde-3-phosphate = 2 µM
Refer to Exhibit 6A. "Restrainin" is an inhibitor of triose phosphate isomerase. When it is added to cells at a concentration of 0.4 nM, the enzyme's apparent K_M for the substrate is altered to 100 µM, but the V_max is unchanged.
In the following graph, which line best represents the Lineweaver-Burk plot obtained in the presence of restrainin?

Question

Exhibit 6A This is a reaction going on in your muscle cells right this very minute:

The enzyme triose phosphate isomerase catalyzes this reaction in the forward direction as part of the glycolytic pathway. It follows simple Michaelis-Menten kinetics:

Typical cellular concentrations: triose phosphate isomerase = 0.1 nM
Dihydroxyacetone phosphate = 5 µM glyceraldehyde-3-phosphate = 2 µM
Refer to Exhibit 6A. "Restrainin" is an inhibitor of triose phosphate isomerase. When it is added to cells at a concentration of 0.4 nM, the enzyme's apparent K_M for the substrate is altered to 100 µM, but the V_max is unchanged.
In the following graph, which line best represents the Lineweaver-Burk plot obtained in the presence of restrainin?

Quizplus · Accepted Answer

The Answer of Exhibit 6A This is a reaction going on in your muscle cells right this very minute: The enzyme triose phosphate isomerase catalyzes this reaction in the forward direction as part of the glycolytic pathway. It follows simple Michaelis-Menten kinetics: Typical cellular concentrations: triose phosphate isomerase = 0.1 nM Dihydroxyacetone phosphate = 5 µM glyceraldehyde-3-phosphate = 2 µM Refer to Exhibit 6A. "Restrainin" is an inhibitor of triose phosphate isomerase. When it is added to cells at a concentration of 0.4 nM, the enzyme's apparent K_M for the substrate is altered to 100 µM, but the V_max is unchanged. In the following graph, which line best represents the Lineweaver-Burk plot obtained in the presence of restrainin?

Exhibit 6A This Is a Reaction Going on in Your