Irreversible inhibitors of enzymatic reactions
A) bind to the enzyme only at low temperatures.
B) affect only serine side chains.
C) react with the enzyme to produce a protein that is not enzymatically active and from which the original enzyme cannot be regenerated.
D) are bound to the enzyme by the lock-and-key mechanism.

Question

Quizplus · Accepted Answer

Irreversible inhibitors chemically modify an enzyme in a way that it cannot be regenerated back to its active form, effectively rendering the enzyme permanently inactive. This does not necessarily depend on temperature, specific amino acid side chains, or the lock-and-key mechanism of enzyme binding.

Irreversible Inhibitors of Enzymatic Reactions