What effect is seen on a Lineweaver-Burk graph when a mixed-type inhibitor is added?
A) The y-intercept is changed, but not change the slope of the line.
B) The slope of the line is changed, but not the y-intercept.
C) Both the y-intercept and the slope of the line are changed.
D) Neither the y-intercept not the slope of the line is changed.

Question

Quizplus · Accepted Answer

Mixed-type inhibitors affect both the Km and Vmax of an enzyme, which on a Lineweaver-Burk plot translates to changes in both the slope (which represents Km/Vmax) and the y-intercept (which represents 1/Vmax).

What Effect Is Seen on a Lineweaver-Burk Graph When a Mixed-Type