The sequential model for allosteric behavior
A) cannot account for reactions that display negative cooperativity.
B) postulates binding of substrates and inhibitors by the induced-fit model.
C) requires that the conformation of all subunits change simultaneously.
D) is mathematically simpler than the concerted model.

Question

Quizplus · Accepted Answer

The sequential model, also known as the KNF model, suggests that substrate binding induces a conformational change in one subunit, which then affects the neighboring subunits, aligning with the induced-fit model.

The Sequential Model for Allosteric Behavior