RNA is hydrolyzed in basic solution, but DNA is not. This occurs because
A) thymine is found in DNA, and uracil is not
B) DNA is double stranded, and RNA is single stranded
C) DNA contains 2'-deoxyribose, but RNA does not
D) RNA has modified bases, but DNA does not

Question

Quizplus · Accepted Answer

DNA contains 2'-deoxyribose sugar, which lacks the hydroxyl group at the 2' position found in RNA's ribose sugar. This hydroxyl group in RNA makes it more susceptible to hydrolysis in basic conditions, as it is more reactive.

RNA Is Hydrolyzed in Basic Solution, but DNA Is Not