How do the core enzyme and the holoenzyme of RNA polymerase differ in E. coli ?
A) The holoenzyme includes the sigma ( σ ) subunit, the core enzyme does not.
B) The core enzyme includes the sigma ( σ ) subunit, the holoenzyme does not.
C) The holoenzyme transcribes from an RNA template, the core enzyme from a DNA template.
D) The core enzyme transcribes from an RNA template, the holoenzyme from a DNA template.

Question

Quizplus · Accepted Answer

The holoenzyme of RNA polymerase in E. coli includes the sigma (σ) subunit, which is responsible for promoter recognition and is not present in the core enzyme. The core enzyme, lacking the σ subunit, is unable to initiate transcription on its own.

How Do the Core Enzyme and the Holoenzyme of RNA