Chain termination occurs, in vivo , when:
A) RNA Polymerase gets to the end of the DNA.
B) The factor called rho ( ρ ) binds to the DNA.
C) A hairpin loop forms in the template.
D) Either a hairpin loop forms or rho ( ρ ) catches up with transcription stalled by a hairpin loop
E) None of these

Question

Quizplus · Accepted Answer

Chain termination in vivo can occur through two primary mechanisms: the rho-dependent mechanism, where the rho factor catches up with the RNA polymerase that has stalled at a hairpin loop, and the rho-independent mechanism, where a hairpin loop forms in the RNA, causing the polymerase to pause and eventually dissociate from the DNA. Both mechanisms involve the formation of a hairpin loop, with the rho-dependent mechanism also requiring the action of the rho factor.

Chain Termination Occurs, in Vivo , When