A biological reaction with a significantly postive Δ G under cellular conditions may proceed in the forward direction because
A) The cell will change the concentrations of the substrates and products so that the reaction can occur
B) The cell will raise the temperature, thereby affecting the overall thermodynamics of the reaction
C) the reaction can be coupled to a reaction with a more significant negative Δ G
D) reactions with positive Δ G values always proceed in the forward direction
E) None of these

Question

Quizplus · Accepted Answer

Reactions with a positive ΔG (Gibbs free energy change) indicate that they are not spontaneous under standard conditions. However, cells can drive such reactions forward by coupling them to other reactions that release a larger amount of energy (negative ΔG), making the overall process energetically favorable. This is a common strategy in metabolic pathways.

A Biological Reaction with a Significantly Postive Δ G Under