The reaction of the citric acid cycle that does not take place in the mitochondrial matrix is the one catalyzed by:
A) fumarase
B) citrate synthase
C) isocitrate dehydrogenase
D) succinate dehydrogenase
E) All of these reactions take place in the matrix

Question

Quizplus · Accepted Answer

Succinate dehydrogenase is unique among the citric acid cycle enzymes because it is embedded in the inner mitochondrial membrane, where it also participates in the electron transport chain, unlike the other enzymes listed which all operate within the mitochondrial matrix.

The Reaction of the Citric Acid Cycle That Does Not