The conversion of malate to oxaloacetate has a high + Δ G (it is endergonic). It can take place because:
A) It is coupled to hydrolysis of the GTP produce earlier in the cycle.
B) It is coupled to hydrolysis of ATP from other sources.
C) It involves a substrate level phosphorylation.
D) The oxaloacetate product is used up in the subsequent reaction.
E) It is coupled to a strong reduction reaction.

Question

Quizplus · Accepted Answer

The conversion of malate to oxaloacetate is driven forward because the oxaloacetate is continuously used up in the subsequent reaction of the citric acid cycle, keeping its concentration low and pulling the reaction forward.

The Conversion of Malate to Oxaloacetate Has a High