The production of malate in the glyoxylate pathway is important, since it can be readily converted to phosphoenolpyruvate and then to sugars.

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In the glyoxylate cycle, malate can be converted into oxaloacetate, which can then be used to generate phosphoenolpyruvate (PEP) through the action of PEP carboxykinase. PEP is a key intermediate in gluconeogenesis, the pathway that synthesizes glucose from non-carbohydrate precursors, thus enabling the conversion of fats (acetyl-CoA) into sugars.

The Production of Malate in the Glyoxylate Pathway Is Important