Uncouplers are compounds that inhibit the phosphorylation of ADP
A) by enhancing the proton gradient across the outer mitochondrial membrane.
B) by enhancing the proton gradient across the inner mitochondrial membrane.
C) because they are transmembrane proteins in the outer mitochondrial membrane.
D) without affecting electron transport.

Question

Quizplus · Accepted Answer

Uncouplers disrupt the proton gradient across the inner mitochondrial membrane, allowing protons to flow back into the mitochondrial matrix without generating ATP, but they do not inhibit the electron transport chain itself.

Uncouplers Are Compounds That Inhibit the Phosphorylation of ADP