How many NADPH are oxidized in the synthesis of palmitoyl-CoA from eight molecules of acetyl-CoA?

Question

Quizplus · Accepted Answer

The synthesis of palmitoyl-CoA from eight molecules of acetyl-CoA involves the fatty acid synthesis cycle, which requires 2 molecules of NADPH for each cycle of elongation (except the first acetyl-CoA). Since palmitate is a 16-carbon fatty acid, 7 cycles of elongation are needed after the initial condensation, requiring 14 NADPH in total.

How Many NADPH Are Oxidized in the Synthesis of Palmitoyl-CoA