Which conflict over religion sprang from the Protestant Reformation?

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The Thirty Years' War, which took place from 1618 to 1648, was a conflict primarily fought in Central Europe and was one of the most destructive wars in European history. It began as a battle among Catholic and Protestant states in the fragmented Holy Roman Empire and gradually developed into a more general conflict involving most of the great powers of the time, reflecting the broader tensions between the Protestant Reformation and the Counter-Reformation led by the Catholic Church.

Which Conflict Over Religion Sprang from the Protestant Reformation