What Was the Significance of Puerto Rico During Spanish Exploration

What was the significance of Puerto Rico during Spanish exploration?

A) It was where the Indians revolted and booted out the Spanish.
B) It was rare among European colonies in that it had gold.
C) It later broke away from Spain and became an independent nation.
D) Under Spanish rule, slavery was outlawed and all residents had equal rights.
E) Natives in this colony were immune to European diseases.