Fragile X syndrome is a genetic condition that affects males more severely and is characterized by learning disabilities, attention issues, and hyperactivity. It is caused by a mutation in the FMR1 gene on the X chromosome, not the Y chromosome, and involves an expansion of CGG repeats, not a deletion. It is inherited in an X-linked dominant pattern and is not due to genomic imprinting.

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Fragile X Syndrome

Question 35

Multiple Choice

Fragile X syndrome:

A) results in learning, attention, and hyperactivity disabilities in males
B) is not inherited from the parents
C) is characterized by a fragile site at the tip of the Y chromosome
D) results from a deletion of CGG sequences in the fragile X gene
E) is due to genomic imprinting

Correct Answer: