In individuals with cystic fibrosis:

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In individuals with cystic fibrosis, the gene that codes for a protein that regulates the movement of salt in and out of cells is mutated. This leads to thick, sticky mucus production throughout the body, including the lungs, pancreas, liver, intestines, sinuses, and sex organs. This abnormal mucous secretion is a hallmark of the disease, affecting various body systems, not just the respiratory system. The mucus does not enhance cilia action, prevent bacterial growth, or inhibit infections; in fact, it can obstruct airways, trap bacteria leading to infections, and cause complications in other organs.

In Individuals with Cystic Fibrosis