Which of the Following Best Defines the Bohr Effect

Which of the following best defines the Bohr effect?

A) The amount of a gas that diffuses across a membrane depends on the differences in the gas's partial pressure.
B) The ability of hemoglobin to bind oxygen depends on the partial pressure of oxygen.
C) In a mixture of gases, the total pressure of the mixture is the sum of the pressures of the individual gases.
D) pH causes a displacement of the oxygen-hemoglobin dissociation curve.
E) As the concentration of chloride ions increases, the ability of hemoglobin to bind carbon dioxide decreases.