Mouse pigmentation is subject to epistasis of the B alleles by the d alleles. B (black)is dominant over b (brown), and D is dominant over d . Homozygous d is epistatic to the black and brown genes. Given this information, what will result from a F₁ cross between two mice?

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Epistasis of the B alleles by the d alleles means that the d allele is epistatic to the B allele. This means that the d allele will mask the expression of the B allele. In this case, the d allele is homozygous, which means that all of the mice will have the white phenotype.

Mouse Pigmentation Is Subject to Epistasis of the B Alleles