A Key Difference Between Eukaryotic and Prokaryotic Genomes Is ____

A key difference between eukaryotic and prokaryotic genomes is ____. ​

A) the lack of gene expression controls in prokaryotes
B) the physical arrangement of genes on the chromosome(s)
C) simultaneous transcription and translation in eukaryotes vs. sequential transcription and translation in prokaryotes
D) the physical separation of transcription and translation in prokaryotes compared to the lack of separation of these processes in eukaryotes
E) the regulation of the cell cycle by eukaryotes which is not observed in prokaryotes.