The Pattern of Gene Transfer from Hfr to F- Cells

The pattern of gene transfer from Hfr to F- cells ____. ​

A) occurs with genes furthest from the F factor being transferred first
B) can be used to map chromosomal genes in the F- cell ​
C) was used to map the E. coli chromosome ​
D) cannot be used to indicate the relative positions of genes within the Hfr cell ​
E) is random because the F factor moves between different positions in the chromosome ​