Cystic fibrosis is a recessive disorder. If a couple, each of whom is heterozygous for the CFTR mutation, have children, what is the probability that they will have a child with cystic fibrosis?

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When both parents are heterozygous for a recessive disorder like cystic fibrosis, there is a 25% chance for each child to inherit two copies of the mutated gene (one from each parent), resulting in the child having cystic fibrosis.

Cystic Fibrosis Is a Recessive Disorder