When the H⁺concentration Is Significantly Higher in the Mitochondrial Matrix

When the H⁺concentration is significantly higher in the mitochondrial matrix than the intermembrane space, ATP synthase would ____.

A) require an ion to stabilize it
B) no longer function properly
C) hydrolyze ATP to form ADP to pump protons out of the matrix
D) generate ATP to pump protons into the matrix
E) be uncoupled from the electron transport chain