How is the NO pathway manipulated by Viagra to treat erectile dysfunction?
A) NO synthesis is decreased
B) NO synthesis is increased
C) the enzyme catalyzed by NO is stabilized
D) the enzyme catalyzed by NO is inhibited
E) the breakdown of cGMP is inhibited

Question

Quizplus · Accepted Answer

Viagra (sildenafil) works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which breaks down cyclic guanosine monophosphate (cGMP). cGMP is a molecule that is increased in response to nitric oxide (NO) and is responsible for relaxing smooth muscle cells, allowing for increased blood flow. By inhibiting the breakdown of cGMP, Viagra effectively enhances the effects of NO, leading to improved erectile function.

How Is the NO Pathway Manipulated by Viagra to Treat