Colchicine, a chemical extracted from the autumn crocus (C olchicum autumnale ), inhibits the formation of microtubules. Mitotic cells exposed to colchicine will therefore be arrested at ____.
A) anaphase
B) interphase
C) prophase
D) telophase
E) metaphase

Question

Quizplus · Accepted Answer

Colchicine prevents the formation of the mitotic spindle by inhibiting microtubule polymerization. This action arrests cells in metaphase because chromosomes cannot align properly at the metaphase plate without a functional spindle.

Colchicine, a Chemical Extracted from the Autumn Crocus (C Olchicum