You are a genetic counselor, and a couple comes to you with concerns that if they have a child together, he or she could have hemophilia. The woman has an X-linked recessive form of hemophilia, but the man does not. How should you advise them?

Question

Quizplus · Accepted Answer

Since the mother has an X-linked recessive form of hemophilia and the father does not, all of their sons will inherit the X chromosome with the hemophilia gene from their mother (since males inherit their X chromosome from their mother and Y chromosome from their father), and all of their daughters will inherit one X chromosome with the hemophilia gene from their mother and a normal X chromosome from their father, making them carriers.

You Are a Genetic Counselor, and a Couple Comes to You