The anterior pituitary secretes more ACTH, leading to more glucocorticoids in plasma, which causes the anterior pituitary to then secrete less ACTH. This is an example of ____ regulation.
A) amplification only
B) positive feedback only
C) negative feedback
D) cascading feedback
E) both amplification and positive feedback

Question

Quizplus · Accepted Answer

This is an example of negative feedback because the initial increase in ACTH leads to an increase in glucocorticoids, which then suppress further ACTH secretion from the anterior pituitary, thus reducing the signal that initiated the response. This mechanism helps maintain homeostasis by preventing excessive hormone levels.

The Anterior Pituitary Secretes More ACTH, Leading to More Glucocorticoids