By the time symptoms of type 1 diabetes develop, damage to the beta cells has often occurred and the first sign of the disease is:

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Quizplus · Accepted Answer

By the time symptoms develop, the beta cells have already been damaged, leading to a lack of insulin production and resulting in high levels of glucose in the blood (hyperglycemia). Hypoglycemia, high blood lipids, and microalbuminuria can also be symptoms or complications of diabetes, but they are not typically the first sign of the disease. The last option appears to be a typo and is not a valid choice.

By the Time Symptoms of Type 1 Diabetes Develop, Damage