What is thought to promote the development of brain senile plaques and neurofibrillary tangles?

Question

What is thought to promote the development of brain senile plaques and neurofibrillary tangles? ​

Quizplus · Accepted Answer

Oxidative stress is thought to promote the development of brain senile plaques and neurofibrillary tangles, which are hallmark features of Alzheimer's disease. Oxidative stress occurs when there is an imbalance between the production of reactive oxygen species and the antioxidant defense system, leading to damage to cellular structures such as proteins, lipids, and DNA. This damage has been linked to the development and progression of Alzheimer's disease.

What Is Thought to Promote the Development of Brain Senile