PS is an 87-year-old male admitted to a hospital for stomach pain. He has mild breathing problems and complains of fatigue and chronic stomach upset, for which he takes a daily antacid. While hospitalized, a physician has determined that PS has megaloblastic anemia.
-Given PS's age and symptoms, what is a likely cause of the megaloblastic anemia?

Question

Quizplus · Accepted Answer

PS's chronic stomach upset and use of antacids suggest that he may have reduced absorption of vitamin B12 due to inadequate intrinsic factor. This can lead to megaloblastic anemia, which is characterized by large, immature red blood cells. Folate deficiency can also cause megaloblastic anemia, but since PS takes a daily antacid, it is more likely that his anemia is due to reduced absorption of vitamin B12. Liver disease or lead poisoning can cause anemia, but they would not typically result in megaloblastic anemia specifically. Excessive loss of blood from a stomach ulcer could lead to iron-deficiency anemia, but not megaloblastic anemia.

PS Is an 87-Year-Old Male Admitted to a Hospital for Stomach