The primary immune response normally begins with the proliferation of memory cells, which can be sufficient to block infection if virulence of the pathogens is low.

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The primary immune response begins with the proliferation of B cells specific to the pathogen. It takes time for these cells to differentiate into plasma cells that can produce antibodies. Memory cells are produced after the primary immune response and are responsible for a more rapid and effective response upon subsequent exposure to the same pathogen.

The Primary Immune Response Normally Begins with the Proliferation of Memory